NHERF1 acts as a molecular switch to program metastatic behavior and organotropism via its PDZ domains

Metastatic cells are highly plastic for differential expression of tumor phenotype hallmarks and metastatic organotropism. The signaling proteins orchestrating the shift of one cell phenotype and organ pattern to another are little known. Na(+)/H(+) exchanger regulatory factor (NHERF1) is a molecula...

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Detalhes bibliográficos
Main Authors: Cardone, Rosa Angela, Greco, Maria Raffaella, Capulli, Mattia, Weinman, Edward J., Busco, Giovanni, Bellizzi, Antonia, Casavola, Valeria, Antelmi, Ester, Ambruosi, Barbara, Dell'Aquila, Maria Elena, Paradiso, Angelo, Teti, Anna, Rucci, Nadia, Reshkin, Stephan Joel
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364169/
https://ncbi.nlm.nih.gov/pubmed/22496422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-11-0911
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