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NHERF1 acts as a molecular switch to program metastatic behavior and organotropism via its PDZ domains
Metastatic cells are highly plastic for differential expression of tumor phenotype hallmarks and metastatic organotropism. The signaling proteins orchestrating the shift of one cell phenotype and organ pattern to another are little known. Na(+)/H(+) exchanger regulatory factor (NHERF1) is a molecula...
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| 主要な著者: | , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Cell Biology
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3364169/ https://ncbi.nlm.nih.gov/pubmed/22496422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-11-0911 |
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