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Monoubiquitylation promotes mitochondrial p53 translocation
A major function of the p53 tumor suppressor is the induction of a pleiotropic apoptotic program in response to stress through transcription-dependent and -independent mechanisms. In particular, this includes a direct apoptotic role of p53 at the mitochondria. Stress-induced p53 translocation to the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852828/ https://ncbi.nlm.nih.gov/pubmed/17268548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601560 |
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