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p53 opens the mitochondrial permeability transition pore to trigger necrosis

Ischemia-associated oxidative damage leading to necrosis is a major cause of catastrophic tissue loss in human health. Elucidating its signaling mechanism is of paramount importance. p53 is a central stress sensor responding to multiple insults including oxidative stress to orchestrate apoptotic and...

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Detaylı Bibliyografya
Asıl Yazarlar: Vaseva, Angelina V., Marchenko, Natalia D., Ji, Kyungmin, Tsirka, Stella E., Holzmann, Sonja, Moll, Ute M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383624/
https://ncbi.nlm.nih.gov/pubmed/22726440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.05.014
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