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Monoubiquitylation promotes mitochondrial p53 translocation

A major function of the p53 tumor suppressor is the induction of a pleiotropic apoptotic program in response to stress through transcription-dependent and -independent mechanisms. In particular, this includes a direct apoptotic role of p53 at the mitochondria. Stress-induced p53 translocation to the...

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Bibliografske podrobnosti
Main Authors: Marchenko, Natasha D, Wolff, Sonja, Erster, Susan, Becker, Kerstin, Moll, Ute M
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852828/
https://ncbi.nlm.nih.gov/pubmed/17268548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601560
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