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Granulocyte colony-stimulating factor enhances bone tumor growth in mice in an osteoclast-dependent manner

Inhibition of osteoclast (OC) activity has been associated with decreased tumor growth in bone in animal models. Increased recognition of factors that promote osteoclastic bone resorption in cancer patients led us to investigate whether increased OC activation could enhance tumor growth in bone. Gra...

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Hlavní autoři: Hirbe, Angela C., Uluçkan, Özge, Morgan, Elizabeth A., Eagleton, Mark C., Prior, Julie L., Piwnica-Worms, David, Trinkaus, Kathryn, Apicelli, Anthony, Weilbaecher, Katherine
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852257/
https://ncbi.nlm.nih.gov/pubmed/17192391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-09-048686
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