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Granulocyte colony-stimulating factor enhances bone tumor growth in mice in an osteoclast-dependent manner

Inhibition of osteoclast (OC) activity has been associated with decreased tumor growth in bone in animal models. Increased recognition of factors that promote osteoclastic bone resorption in cancer patients led us to investigate whether increased OC activation could enhance tumor growth in bone. Gra...

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Autori principali: Hirbe, Angela C., Uluçkan, Özge, Morgan, Elizabeth A., Eagleton, Mark C., Prior, Julie L., Piwnica-Worms, David, Trinkaus, Kathryn, Apicelli, Anthony, Weilbaecher, Katherine
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852257/
https://ncbi.nlm.nih.gov/pubmed/17192391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-09-048686
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