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Granulocyte colony-stimulating factor enhances bone tumor growth in mice in an osteoclast-dependent manner

Inhibition of osteoclast (OC) activity has been associated with decreased tumor growth in bone in animal models. Increased recognition of factors that promote osteoclastic bone resorption in cancer patients led us to investigate whether increased OC activation could enhance tumor growth in bone. Gra...

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Detalhes bibliográficos
Main Authors: Hirbe, Angela C., Uluçkan, Özge, Morgan, Elizabeth A., Eagleton, Mark C., Prior, Julie L., Piwnica-Worms, David, Trinkaus, Kathryn, Apicelli, Anthony, Weilbaecher, Katherine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852257/
https://ncbi.nlm.nih.gov/pubmed/17192391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-09-048686
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