APT102, a Novel ADPase, Cooperates With Aspirin to Disrupt Bone Metastasis in Mice

Platelets contribute to the development of metastasis, the most common cause of mortality in cancer patients, but the precise role that anti-platelet drugs play in cancer treatment is not defined. Metastatic tumor cells can produce platelet aIIbb3 activators, such as ADP and thromboxane A(2) (TXA(2)...

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Hlavní autoři: Uluçkan, Özge, Eagleton, Mark C., Floyd, Desiree H., Morgan, Elizabeth A., Hirbe, Angela C., Kramer, Matthew, Dowland, Nikki, Prior, Julie L., Piwnica-Worms, David, Jeong, Soon Seog, Chen, Ridong, Weilbaecher, Katherine
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763643/
https://ncbi.nlm.nih.gov/pubmed/18260128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21709
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