APT102, a Novel ADPase, Cooperates With Aspirin to Disrupt Bone Metastasis in Mice

Platelets contribute to the development of metastasis, the most common cause of mortality in cancer patients, but the precise role that anti-platelet drugs play in cancer treatment is not defined. Metastatic tumor cells can produce platelet aIIbb3 activators, such as ADP and thromboxane A(2) (TXA(2)...

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Autores principales: Uluçkan, Özge, Eagleton, Mark C., Floyd, Desiree H., Morgan, Elizabeth A., Hirbe, Angela C., Kramer, Matthew, Dowland, Nikki, Prior, Julie L., Piwnica-Worms, David, Jeong, Soon Seog, Chen, Ridong, Weilbaecher, Katherine
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763643/
https://ncbi.nlm.nih.gov/pubmed/18260128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21709
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