Safety and Allele-Specific Immunogenicity of a Malaria Vaccine in Malian Adults: Results of a Phase I Randomized Trial

OBJECTIVES: The objectives were to evaluate the safety, reactogenicity, and allele-specific immunogenicity of the blood-stage malaria vaccine FMP1/AS02A in adults exposed to seasonal malaria and the impact of natural infection on vaccine-induced antibody levels. DESIGN: We conducted a randomized, do...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Thera, Mahamadou A, Doumbo, Ogobara K, Coulibaly, Drissa, Diallo, Dapa A, Sagara, Issaka, Dicko, Alassane, Diemert, David J, Heppner, D. Gray, Stewart, V. Ann, Angov, Evelina, Soisson, Lorraine, Leach, Amanda, Tucker, Kathryn, Lyke, Kirsten E, Plowe, Christopher V
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2006
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851722/
https://ncbi.nlm.nih.gov/pubmed/17124530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pctr.0010034
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