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Strain-specific Plasmodium falciparum growth inhibition among Malian children immunized with a blood-stage malaria vaccine

The blood-stage malaria vaccine FMP2.1/AS02A, comprised of recombinant Plasmodium falciparum apical membrane antigen 1 (AMA1) and the adjuvant system AS02A, had strain-specific efficacy against clinical malaria caused by P. falciparum with the vaccine strain 3D7 AMA1 sequence. To evaluate a potentia...

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Veröffentlicht in:PLoS One
Hauptverfasser: Laurens, Matthew B., Kouriba, Bourema, Bergmann-Leitner, Elke, Angov, Evelina, Coulibaly, Drissa, Diarra, Issa, Daou, Modibo, Niangaly, Amadou, Blackwelder, William C., Wu, Yukun, Cohen, Joe, Ballou, W. Ripley, Vekemans, Johan, Lanar, David E., Dutta, Sheetij, Diggs, Carter, Soisson, Lorraine, Heppner, D. Gray, Doumbo, Ogobara K., Plowe, Christopher V., Thera, Mahamadou A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345808/
https://ncbi.nlm.nih.gov/pubmed/28282396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173294
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