Malaria severity: Possible influence of the E670G PCSK9 polymorphism: A preliminary case-control study in Malian children

AIM: Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a hepatic secretory protein which promotes the degradation of low-density lipoprotein receptors leading to reduced hepatic uptake of plasma cholesterol. Non-synonymous single-nucleotide polymorphisms in its gene have been linked to hypo-...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Arama, Charles, Diarra, Issa, Kouriba, Bourèma, Sirois, Francine, Fedoryak, Olesya, Thera, Mahamadou A., Coulibaly, Drissa, Lyke, Kirsten E., Plowe, Christopher V., Chrétien, Michel, Doumbo, Ogobara K., Mbikay, Majambu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813955/
https://ncbi.nlm.nih.gov/pubmed/29447211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192850
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