Safety and Allele-Specific Immunogenicity of a Malaria Vaccine in Malian Adults: Results of a Phase I Randomized Trial

OBJECTIVES: The objectives were to evaluate the safety, reactogenicity, and allele-specific immunogenicity of the blood-stage malaria vaccine FMP1/AS02A in adults exposed to seasonal malaria and the impact of natural infection on vaccine-induced antibody levels. DESIGN: We conducted a randomized, do...

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Autori principali: Thera, Mahamadou A, Doumbo, Ogobara K, Coulibaly, Drissa, Diallo, Dapa A, Sagara, Issaka, Dicko, Alassane, Diemert, David J, Heppner, D. Gray, Stewart, V. Ann, Angov, Evelina, Soisson, Lorraine, Leach, Amanda, Tucker, Kathryn, Lyke, Kirsten E, Plowe, Christopher V
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2006
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851722/
https://ncbi.nlm.nih.gov/pubmed/17124530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pctr.0010034
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