Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency

CD1d-restricted natural killer T (NKT) cells, expressing the invariant T cell antigen receptor (TCR) chain encoded by Vα14-Jα18 gene segments in mice and Vα24-Jα18 in humans [invariant NKT (iNKT) cells], contribute to immunoregulatory processes, such as tolerance, host defense, and tumor surveillanc...

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Hlavní autoři: Porubsky, Stefan, Speak, Anneliese O., Luckow, Bruno, Cerundolo, Vincenzo, Platt, Frances M., Gröne, Hermann-Josef
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851602/
https://ncbi.nlm.nih.gov/pubmed/17372206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611139104
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