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Globosides but not isoglobosides can impact the development of invariant natural killer T cells and their interaction with dendritic cells
Recognition of endogenous lipid antigen(s) on CD1d is required for the development of invariant natural killer T (iNKT) cells. Isoglobotrihexosylceramide (iGb3) has been implicated as this endogenous selecting ligand and recently suggested to control over-stimulation and deletion of iNKT cells in α-...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3442250/ https://ncbi.nlm.nih.gov/pubmed/22875802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201483 |
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