Globosides but not isoglobosides can impact the development of invariant natural killer T cells and their interaction with dendritic cells

Recognition of endogenous lipid antigen(s) on CD1d is required for the development of invariant natural killer T (iNKT) cells. Isoglobotrihexosylceramide (iGb3) has been implicated as this endogenous selecting ligand and recently suggested to control over-stimulation and deletion of iNKT cells in α-...

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Autores principales: Porubsky, Stefan, Speak, Anneliese O., Salio, Mariolina, Jennemann, Richard, Bonrouhi, Mahnaz, Zafarulla, Rashad, Singh, Yogesh, Dyson, Julian, Luckow, Bruno, Lehuen, Agnes, Malle, Ernst, Müthing, Johannes, Platt, Frances M., Cerundolo, Vincenzo, Gröne, Hermann-Josef
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442250/
https://ncbi.nlm.nih.gov/pubmed/22875802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201483
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