Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals

Development of invariant natural killer T (iNKT) cells requires the presentation of lipid ligand(s) by CD1d molecules in the thymus. The glycosphingolipid (GSL) isoglobotrihexosylceramide (iGb3) has been proposed as the natural iNKT cell-selecting ligand in the thymus and to be involved in periphera...

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Bibliografski detalji
Glavni autori: Speak, Anneliese O., Salio, Mariolina, Neville, David C. A., Fontaine, Josette, Priestman, David A., Platt, Nick, Heare, Tanya, Butters, Terry D., Dwek, Raymond A., Trottein, Francois, Exley, Mark A., Cerundolo, Vincenzo, Platt, Frances M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851601/
https://ncbi.nlm.nih.gov/pubmed/17372214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607285104
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