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Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals
Development of invariant natural killer T (iNKT) cells requires the presentation of lipid ligand(s) by CD1d molecules in the thymus. The glycosphingolipid (GSL) isoglobotrihexosylceramide (iGb3) has been proposed as the natural iNKT cell-selecting ligand in the thymus and to be involved in periphera...
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| Главные авторы: | , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1851601/ https://ncbi.nlm.nih.gov/pubmed/17372214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607285104 |
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