Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases

Glycolipid ligands for invariant natural killer T cells (iNKT cells) are loaded onto CD1d molecules in the late endosome/lysosome. Accumulation of glycosphingolipids (GSLs) in lysosomal storage diseases could potentially influence endogenous and exogenous lipid loading and/or presentation and, thus,...

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Hauptverfasser: Gadola, Stephan D., Silk, Jonathan D., Jeans, Aruna, Illarionov, Petr A., Salio, Mariolina, Besra, Gurdyal S., Dwek, Raymond, Butters, Terry D., Platt, Frances M., Cerundolo, Vincenzo
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2006
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118110/
https://ncbi.nlm.nih.gov/pubmed/16982810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060921
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