Caspase-3-Dependent Cleavage of the Glutamate-l-Cysteine Ligase Catalytic Subunit during Apoptotic Cell Death

Apoptotic cell death is usually accompanied by activation of a family of cysteine proteases termed caspases. Caspases mediate the selective proteolysis of multiple cellular targets often resulting in the disruption of survival pathways. Intracellular levels of the antioxidant glutathione (GSH) are a...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Franklin, Christopher C., Krejsa, Cecile M., Pierce, Robert H., White, Collin C., Fausto, Nelson, Kavanagh, Terrance J.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2002
Sujets:
Regular Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850882/
https://ncbi.nlm.nih.gov/pubmed/12000740
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