The Catalytic Subunit of Drosophila Glutamate-Cysteine Ligase Is a Nucleocytoplasmic Shuttling Protein

GSH concentration is considerably lower in the nucleus than in the cytoplasm; however, it is significantly elevated during active cell proliferation. The main purpose of this study was to understand the mechanism underlying these variations in nuclear/cytoplasmic distribution of GSH. The rate-limiti...

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Bibliografiske detaljer
Main Authors: Radyuk, Svetlana N., Rebrin, Igor, Luchak, James M., Michalak, Katarzyna, Klichko, Vladimir I., Sohal, Rajindar S., Orr, William C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Metabolism and Bioenergetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629095/
https://ncbi.nlm.nih.gov/pubmed/19036725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805913200
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