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Effects of ectopic expression of Drosophila DNA glycosylases dOgg1 and RpS3 in mitochondria

The main purpose of this study was to determine whether enhancement of repair capacity would attenuate mitochondrial DNA oxidative damage and result in greater cell survival under stressful conditions. The repair of oxidative damage is initiated by DNA glycosylases, which catalyze the excision of ox...

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Autors principals: Radyuk, Svetlana N., Michalak, Katarzyna, Rebrin, Igor, Sohal, Rajindar S., Orr, William C.
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835572/
https://ncbi.nlm.nih.gov/pubmed/16895796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2006.05.021
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