Caspase-3-Dependent Cleavage of the Glutamate-l-Cysteine Ligase Catalytic Subunit during Apoptotic Cell Death

Apoptotic cell death is usually accompanied by activation of a family of cysteine proteases termed caspases. Caspases mediate the selective proteolysis of multiple cellular targets often resulting in the disruption of survival pathways. Intracellular levels of the antioxidant glutathione (GSH) are a...

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Main Authors: Franklin, Christopher C., Krejsa, Cecile M., Pierce, Robert H., White, Collin C., Fausto, Nelson, Kavanagh, Terrance J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2002
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Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850882/
https://ncbi.nlm.nih.gov/pubmed/12000740
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