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Deficiency of Microvascular Thrombomodulin and Up-Regulation of Protease-Activated Receptor-1 in Irradiated Rat Intestine : Possible Link Between Endothelial Dysfunction and Chronic Radiation Fibrosis

Microvascular injury is believed to be mechanistically involved in radiation fibrosis, but direct molecular links between endothelial dysfunction and radiation fibrosis have not been established in vivo. We examined radiation-induced changes in endothelial thrombomodulin (TM) and protease-activated...

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Detalhes bibliográficos
Main Authors: Wang, Junru, Zheng, Huaien, Ou, Xuemei, Fink, Louis M., Hauer-Jensen, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850827/
https://ncbi.nlm.nih.gov/pubmed/12057911
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