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Involvement of heat shock factor 1 in statin-induced transcriptional upregulation of endothelial thrombomodulin
Statins upregulate endothelial thrombomodulin (TM) by mechanisms that involve members of the Kruppel-like factor (KLF) family. While KLFs are unequivocally implicated in this process experimental evidence points to additional mechanisms. Deletion/mutation analysis of reporter constructs was used to...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562544/ https://ncbi.nlm.nih.gov/pubmed/18599869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.174607 |
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