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Involvement of heat shock factor 1 in statin-induced transcriptional upregulation of endothelial thrombomodulin

Statins upregulate endothelial thrombomodulin (TM) by mechanisms that involve members of the Kruppel-like factor (KLF) family. While KLFs are unequivocally implicated in this process experimental evidence points to additional mechanisms. Deletion/mutation analysis of reporter constructs was used to...

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Detalhes bibliográficos
Main Authors: Fu, Qiang, Wang, Junru, Boerma, Marjan, Berbée, Maaike, Qiu, Xiaohua, Fink, Louis M., Hauer-Jensen, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562544/
https://ncbi.nlm.nih.gov/pubmed/18599869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.174607
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