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Inactivation of Thrombomodulin by Ionizing Radiation in a Cell-Free System: Possible Implications for Radiation Responses in Vascular Endothelium

BACKGROUND: Normal tissue radiation injury is associated with loss of vascular thromboresistance, notably because of deficient levels of endothelial thrombomodulin (TM). TM is located on the luminal surface of most endothelial cells and serves critical anticoagulant and anti-inflammatory functions....

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Detalhes bibliográficos
Main Authors: Ross, Christopher C., MacLeod, Stewart L., Plaxco, Jason R., Froude, Jeffrey W., Fink, Louis M., Wang, Junru, Stites, Wesley E., Hauer-Jensen, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2568889/
https://ncbi.nlm.nih.gov/pubmed/18363428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR1148.1
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