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Recombinant Thrombomodulin (Solulin) Ameliorates Early Intestinal Radiation Toxicity in a Preclinical Rat Model

Intestinal radiation toxicity occurs during and after abdominopelvic radiotherapy. Endothelial cells play a significant role in modulating radiation-induced intestinal damage. We demonstrated that the endothelial cell surface receptor thrombomodulin (TM), a protein with anticoagulant, antiinflammato...

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Detalhes bibliográficos
Publicado no:Radiat Res
Main Authors: Pathak, Rupak, Wang, Junru, Garg, Sarita, Aykin-Burns, Nukhet, Petersen, Karl-Uwe, Hauer-Jensen, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995594/
https://ncbi.nlm.nih.gov/pubmed/27459702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR14408.1
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