Assessment of RET/PTC Oncogene Activation and Clonality in Thyroid Nodules with Incomplete Morphological Evidence of Papillary Carcinoma : A Search for the Early Precursors of Papillary Cancer

Noninvasive thyroid nodules that exhibit borderline morphological signs of papillary cancer are difficult to diagnose and we do not know if they represent papillary carcinoma precursor lesions. Forty-six such nodules were analyzed for RET activation by immunohistochemistry and, in selected cases, by...

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Hlavní autoři: Fusco, Alfredo, Chiappetta, Gennaro, Hui, Pei, Garcia-Rostan, Ginesa, Golden, Lauren, Kinder, Barbara K., Dillon, Deborah A., Giuliano, Ada, Cirafici, Anna Maria, Santoro, Massimo, Rosai, Juan, Tallini, Giovanni
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2002
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850819/
https://ncbi.nlm.nih.gov/pubmed/12057919
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