Assessment of RET/PTC Oncogene Activation and Clonality in Thyroid Nodules with Incomplete Morphological Evidence of Papillary Carcinoma : A Search for the Early Precursors of Papillary Cancer

Noninvasive thyroid nodules that exhibit borderline morphological signs of papillary cancer are difficult to diagnose and we do not know if they represent papillary carcinoma precursor lesions. Forty-six such nodules were analyzed for RET activation by immunohistochemistry and, in selected cases, by...

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Autori principali: Fusco, Alfredo, Chiappetta, Gennaro, Hui, Pei, Garcia-Rostan, Ginesa, Golden, Lauren, Kinder, Barbara K., Dillon, Deborah A., Giuliano, Ada, Cirafici, Anna Maria, Santoro, Massimo, Rosai, Juan, Tallini, Giovanni
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2002
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850819/
https://ncbi.nlm.nih.gov/pubmed/12057919
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