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CD28-B7-Mediated T Cell Costimulation in Chronic Cardiac Allograft Rejection : Differential Role of B7–1 in Initiation versus Progression of Graft Arteriosclerosis

Provision of adequate T cell costimulation is critical for the development of acute and chronic allograft rejection. We have previously reported that early blockade of CD28-B7 T cell costimulation prevents the development of graft arteriosclerosis, in the LEW into F344 rat cardiac transplant model....

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Main Authors: Kim, Kyung Soo, Denton, Mark D., Chandraker, Anil, Knoflach, Andreas, Milord, Rolando, Waaga, Anna Maria, Turka, Laurence A., Russell, Mary E., Peach, Robert, Sayegh, Mohamed H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Investigative Pathology 2001
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850369/
https://ncbi.nlm.nih.gov/pubmed/11238045
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