Paradoxical Functions of B7: CD28 Costimulation in a MHC Class II-Mismatched Cardiac Transplant Model

Blockade of the B7: CD28 costimulatory pathway has emerged as a promising therapy to prevent allograft rejection. However, this pathway has also been demonstrated to be important for the generation and maintenance of regulatory T cells. In this study, we investigated the role of the B7: CD28 pathway...

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Bibliografiset tiedot
Päätekijät: Yang, J., Riella, L.V., Boenisch, O., Popoola, J., Robles, S., Watanabe, T., Vanguri, V., Yuan, X., Guleria, I., Turka, L. A., Sayegh, M. H., Chandraker, A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841781/
https://ncbi.nlm.nih.gov/pubmed/19845593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2009.02839.x
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