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MHC class Ib-restricted CD8 T cells differ in dependence on CD4 T cell help and CD28 costimulation over the course of mouse polyomavirus infection()

We recently identified a protective MHC class Ib-restricted CD8 T cell response to infection with mouse polyomavirus. These CD8 T cells recognize a peptide from aa 139–147 of the VP2 viral capsid protein bound to the nonpolymorphic H-2Q9 molecule, a member of the Qa-2 family of β(2)m-associated MHC-...

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Detalhes bibliográficos
Main Authors: Hofstetter, Amelia R., Ford, Mandy L., Sullivan, Lucy C., Wilson, Jarad J., Hadley, Annette, Brooks, Andrew G., Lukacher, Aron E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311765/
https://ncbi.nlm.nih.gov/pubmed/22393155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103554
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