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Late blockade of T cell costimulation interrupts progression of experimental chronic allograft rejection.

Early blockade of T cell-costimulatory activation pathways prevents development of experimental chronic allograft rejection. Ongoing T cell recognition of alloantigen and activation may also play an important role in progression of chronic rejection, but definitive evidence is lacking. We used the f...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Chandraker, A, Azuma, H, Nadeau, K, Carpenter, C B, Tilney, N L, Hancock, W W, Sayegh, M H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508820/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9616202/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI2299
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