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Critical Role of the N-Loop and β1-Strand Hydrophobic Clusters of RANTES-Derived Peptides in Anti-HIV Activity

HIV initiates its infectious cycle by docking to CD4 and a chemokine receptor, most commonly CCR5. RANTES, a natural CCR5 ligand, is a potent inhibitor of HIV-1. Despite the lack of structural information on the RANTES-CCR5 complex, determinants of HIV blockade were previously identified within the...

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Bibliografski detalji
Glavni autori: Vangelista, Luca, Longhi, Renato, Sironi, Francesca, Pavone, Vincenzo, Lusso, Paolo
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850098/
https://ncbi.nlm.nih.gov/pubmed/17083916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.10.090
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