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The Shed Ectodomain of Collagen XVII/BP180 Is Targeted by Autoantibodies in Different Blistering Skin Diseases

Collagen XVII/BP180, an epidermal adhesion molecule, exists as a full-length transmembrane protein and as a soluble 120-kd ectodomain that is shed from the keratinocyte surface by furin-mediated proteolysis. Despite a number of studies on autoantibody targets in blistering skin diseases, it has rema...

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Détails bibliographiques
Auteurs principaux: Schumann, Hauke, Baetge, Jens, Tasanen, Kaisa, Wojnarowska, Fenella, Schäcke, Heike, Zillikens, Detlef, Bruckner-Tuderman, Leena
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850053/
https://ncbi.nlm.nih.gov/pubmed/10666397
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