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Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs

Collagen XVII, a type II transmembrane protein and epithelial adhesion molecule, can be proteolytically shed from the cell surface to generate a soluble collagen. Here we investigated the release of the ectodomain and identified the enzymes involved. After surface biotinylation of keratinocytes, the...

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Detalhes bibliográficos
Main Authors: Franzke, Claus-Werner, Tasanen, Kaisa, Schäcke, Heike, Zhou, Zhongjun, Tryggvason, Karl, Mauch, Cornelia, Zigrino, Paola, Sunnarborg, Susan, Lee, David C., Fahrenholz, Falk, Bruckner-Tuderman, Leena
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC129053/
https://ncbi.nlm.nih.gov/pubmed/12356719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf532
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