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Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs

Collagen XVII, a type II transmembrane protein and epithelial adhesion molecule, can be proteolytically shed from the cell surface to generate a soluble collagen. Here we investigated the release of the ectodomain and identified the enzymes involved. After surface biotinylation of keratinocytes, the...

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Udgivet i:EMBO J
Principais autores: Franzke, Claus-Werner, Tasanen, Kaisa, Schäcke, Heike, Zhou, Zhongjun, Tryggvason, Karl, Mauch, Cornelia, Zigrino, Paola, Sunnarborg, Susan, Lee, David C., Fahrenholz, Falk, Bruckner-Tuderman, Leena
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129053/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12356719/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf532
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