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Shedding of Collagen XVII/BP180 in Skin Depends on Both ADAM10 and ADAM9
Collagen XVII is a transmembrane collagen and the major autoantigen of the autoimmune skin blistering disease bullous pemphigoid. Collagen XVII is proteolytically released from the membrane, and the pathogenic epitope harbors the cleavage site for its ectodomain shedding, suggesting that proteolysis...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749112/ https://ncbi.nlm.nih.gov/pubmed/19574220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.034090 |
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