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Coiled Coils Ensure the Physiological Ectodomain Shedding of Collagen XVII
α-Helical coiled coils, frequent protein oligomerization motifs, are commonly observed in vital proteins. Here, using collagen XVII as an example, we provide evidence for a novel function of coiled coils in the regulation of ectodomain shedding. Transmembrane collagen XVII, an epithelial cell surfac...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436177/ https://ncbi.nlm.nih.gov/pubmed/22761443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.345454 |
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