Coiled Coils Ensure the Physiological Ectodomain Shedding of Collagen XVII

α-Helical coiled coils, frequent protein oligomerization motifs, are commonly observed in vital proteins. Here, using collagen XVII as an example, we provide evidence for a novel function of coiled coils in the regulation of ectodomain shedding. Transmembrane collagen XVII, an epithelial cell surfac...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nishie, Wataru, Jackow, Joanna, Hofmann, Silke C., Franzke, Claus-Werner, Bruckner-Tuderman, Leena
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Protein Structure and Folding
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436177/
https://ncbi.nlm.nih.gov/pubmed/22761443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.345454
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