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Spongiform Neurodegeneration-associated E3 Ligase Mahogunin Ubiquitylates TSG101 and Regulates Endosomal Trafficking

A null mutation in the gene encoding the putative E3 ubiquitin–protein ligase Mahogunin causes spongiform neurodegeneration, a recessively transmitted prion-like disease in mice. However, no substrates of Mahogunin have been identified, and the cellular role of Mahogunin is unknown. Here, we report...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kim, Bong Yoon, Olzmann, James A., Barsh, Gregory S., Chin, Lih-Shen, Li, Lian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838976/
https://ncbi.nlm.nih.gov/pubmed/17229889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-09-0787
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