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SIMPLE: A new regulator of endosomal trafficking and signaling in health and disease
SIMPLE, also known as LITAF, EET1 and PIG7, was originally identified based on its transcriptional upregulation by estrogen, p53, lipopolysaccharide or a microbial cell-wall component. Missense mutations in SIMPLE cause Charcot-Marie-Tooth disease (CMT), and altered SIMPLE expression is associated w...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3656027/ https://ncbi.nlm.nih.gov/pubmed/23713142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.24214 |
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