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TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation

Down-regulation of mitogenic signaling in mammalian cells relies in part on endosomal trafficking of activated receptors into lysosomes, where the receptors are degraded. These events are mediated by ubiquitination of the endosomal cargo and its consequent sorting into multivesicular bodies that for...

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Detalhes bibliográficos
Main Authors: Lu, Quan, Hope, Lila Weiqiao, Brasch, Michael, Reinhard, Christoph, Cohen, Stanley N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164637/
https://ncbi.nlm.nih.gov/pubmed/12802020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0932599100
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