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TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation
Down-regulation of mitogenic signaling in mammalian cells relies in part on endosomal trafficking of activated receptors into lysosomes, where the receptors are degraded. These events are mediated by ubiquitination of the endosomal cargo and its consequent sorting into multivesicular bodies that for...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164637/ https://ncbi.nlm.nih.gov/pubmed/12802020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0932599100 |
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