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TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation

Down-regulation of mitogenic signaling in mammalian cells relies in part on endosomal trafficking of activated receptors into lysosomes, where the receptors are degraded. These events are mediated by ubiquitination of the endosomal cargo and its consequent sorting into multivesicular bodies that for...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lu, Quan, Hope, Lila Weiqiao, Brasch, Michael, Reinhard, Christoph, Cohen, Stanley N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC164637/
https://ncbi.nlm.nih.gov/pubmed/12802020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0932599100
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