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TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation
Down-regulation of mitogenic signaling in mammalian cells relies in part on endosomal trafficking of activated receptors into lysosomes, where the receptors are degraded. These events are mediated by ubiquitination of the endosomal cargo and its consequent sorting into multivesicular bodies that for...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164637/ https://ncbi.nlm.nih.gov/pubmed/12802020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0932599100 |
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