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TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation

Down-regulation of mitogenic signaling in mammalian cells relies in part on endosomal trafficking of activated receptors into lysosomes, where the receptors are degraded. These events are mediated by ubiquitination of the endosomal cargo and its consequent sorting into multivesicular bodies that for...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Proc Natl Acad Sci U S A
Ngā kaituhi matua: Lu, Quan, Hope, Lila Weiqiao, Brasch, Michael, Reinhard, Christoph, Cohen, Stanley N.
Hōputu: Artigo
Reo:Inglês
I whakaputaina: National Academy of Sciences 2003
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164637/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12802020/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0932599100
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