Hypoxia-inducible factor–2 (HIF-2) regulates hepatic erythropoietin in vivo

Erythropoiesis is critically dependent on erythropoietin (EPO), a glycoprotein hormone that is regulated by hypoxia-inducible factor (HIF). Hepatocytes are the primary source of extrarenal EPO in the adult and express HIF-1 and HIF-2, whose roles in the hypoxic induction of EPO remain controversial....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rankin, Erinn B., Biju, Mangatt P., Liu, Qingdu, Unger, Travis L., Rha, Jennifer, Johnson, Randall S., Simon, M. Celeste, Keith, Brian, Haase, Volker H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2007
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838939/
https://ncbi.nlm.nih.gov/pubmed/17404621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30117
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