AT-rich repeats associated with chromosome 22q11.2 rearrangement disorders shape human genome architecture on Yq12

Low copy repeats (LCRs; segmental duplications) constitute ∼5% of the sequenced human genome. Nonallelic homologous recombination events between LCRs during meiosis can lead to chromosomal rearrangements responsible for many genomic disorders. The 22q11.2 region is susceptible to recurrent and nonre...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Babcock, Melanie, Yatsenko, Svetlana, Stankiewicz, Pawel, Lupski, James R., Morrow, Bernice E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2007
Soggetti:
Letter
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1832092/
https://ncbi.nlm.nih.gov/pubmed/17284672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5651507
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi