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AT-rich repeats associated with chromosome 22q11.2 rearrangement disorders shape human genome architecture on Yq12
Low copy repeats (LCRs; segmental duplications) constitute ∼5% of the sequenced human genome. Nonallelic homologous recombination events between LCRs during meiosis can lead to chromosomal rearrangements responsible for many genomic disorders. The 22q11.2 region is susceptible to recurrent and nonre...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1832092/ https://ncbi.nlm.nih.gov/pubmed/17284672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5651507 |
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