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Susceptibility to Heat Stress and Aberrant Gene Expression Patterns in Holocarboxylase Synthetase-deficient Drosophila melanogaster are Caused by Decreased Biotinylation of Histones, not of Carboxylases
Previously we discovered that holocarboxylase synthetase (HCS) is a chromatin-associated protein in Drosophila melanogaster, and that HCS deficiency alters chromatin structure and gene expression patterns, leading to decreased heat tolerance. The effects of HCS deficiency were attributed to decrease...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1832083/ https://ncbi.nlm.nih.gov/pubmed/17374649 |
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