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Susceptibility to Heat Stress and Aberrant Gene Expression Patterns in Holocarboxylase Synthetase-deficient Drosophila melanogaster are Caused by Decreased Biotinylation of Histones, not of Carboxylases

Previously we discovered that holocarboxylase synthetase (HCS) is a chromatin-associated protein in Drosophila melanogaster, and that HCS deficiency alters chromatin structure and gene expression patterns, leading to decreased heat tolerance. The effects of HCS deficiency were attributed to decrease...

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Detalhes bibliográficos
Main Authors: Camporeale, Gabriela, Zempleni, Janos, Eissenberg, Joel C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1832083/
https://ncbi.nlm.nih.gov/pubmed/17374649
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