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Dwell-Time Distribution Analysis of Polyprotein Unfolding Using Force-Clamp Spectroscopy
Using the recently developed single molecule force-clamp technique we quantitatively measure the kinetics of conformational changes of polyprotein molecules at a constant force. In response to an applied force of 110 pN, we measure the dwell times of 1647 unfolding events of individual ubiquitin mod...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1831696/ https://ncbi.nlm.nih.gov/pubmed/17259284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.099481 |
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