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Force-Clamp Spectroscopy of Single-Protein Monomers Reveals the Individual Unfolding and Folding Pathways of I27 and Ubiquitin

Single-protein force experiments have relied on a molecular fingerprint based on tethering multiple single-protein domains in a polyprotein chain. However, correlations between these domains remain an issue in interpreting force spectroscopy data, particularly during protein folding. Here we first s...

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Detalhes bibliográficos
Main Authors: Garcia-Manyes, Sergi, Brujić, Jasna, Badilla, Carmen L., Fernández, Julio M.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965426/
https://ncbi.nlm.nih.gov/pubmed/17545242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.104422
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